Dona solution for intramuscular injection. 200 mg/ml in amp. 2ml per set with solution (diethanolamine, intravenous water in amp. 1 ml) in a pack. No. 6 (glucosamine)

Don's drug belongs to the group of chondroprotectors and serves to protect articular cartilage from destruction. Dona also helps at the initial stage of arthrosis development, when cartilage loses its elasticity and there is a lack of basic elements in the connective tissues - glucosamine and chondroitin. Don's medicine is produced in Italy and Germany, so it has a fairly high price on the Russian market. In this regard, patients are looking for analogues of Don's drug, which help no less effectively, but cost an order of magnitude less.

Analogue drugs are drugs with the same active ingredient as Don's drug. At the same time, analogues may have other excipients that promote rapid absorption of the active component and have a positive effect on the patient’s health. Let's consider substitutes for Don, which can be used to replace this drug, since they have an equivalent effect and contribute to the restoration of cartilage.

pharmachologic effect

Manufacturer: MADAUS GMBH (Germany)
Release form: tablets, capsules, injection solution, powder in bags

Active ingredient: glucosamine

Analogs: Mukosat, Alflutop, Arthra

Dona belongs to the group of stimulators of bone and cartilage tissue repair, which has anti-inflammatory and anesthetic effects. The product stimulates the permeability of the joint capsule, increases the efficiency of enzymatic processes in the structures of cartilage and synovial membrane.

Under the influence of the drug, the process of normalizing calcium deposition in bone tissue, slowing down the progression of degenerative changes in joints, reducing pain and increasing the amplitude of active movements occurs.

Dona - instructions for use

According to the instructions for use of Dona, the medicine is prescribed 1 tablet 2 times a day, mainly during meals, which is washed down with a sufficient volume of water. The duration of the course of therapy can be up to 1.5 months. It is possible to adjust the dosage of the drug upward according to indications.

For intramuscular administration, the product solution is mixed with a solvent in 1 syringe and 3.0 ml is administered 3 times a week for 30–45 days. A packet of powder is dissolved in 200 ml of water and taken once a day for up to 3 months.

Tazan

The drug Tazan is available in tablet form. One tablet contains equal amounts of glucosamine and chondroitin sulfate (500 mg each). As additional substances, the tablets contain silicon dioxide, calcium stearate, potato starch, crospovidone and other agents.

The drug stimulates the regeneration of cartilage tissue, and glucosamine and chondroitin are actively involved in the process of cartilage restoration. When “third-party” glucosamine enters the body, cartilage tissue regulates the production of its own component. Chondroitin stimulates the production of hyaluron, collagen and proteoglycans.

The chondroprotective medicine Tazan is indicated for the treatment of osteoarthritis of the first to third degree. The product is not used for children and patients with problems of the urinary system or kidney diseases. Prescribed with caution for bronchial asthma, bleeding and diabetics.

ADVICE! Tazan is used in adults for three weeks, 1 tablet twice a day. Then the regimen is changed and the use is reduced to one tablet once a day. The therapeutic effect of the drug can be judged after no less than six months.

Tazan is usually well tolerated, but in some patients taking tablets may cause:

Arthra capsules

• tachycardia;
• stomach pain;
• allergic reaction;
• dizziness;
• insomnia;
• drowsiness.

Analogues of Dona

The pharmaceutical market is represented by a large number of analogues of the drug Don, which have a similar therapeutic effect, but may differ in some parameters. You can purchase Dona substitutes at the pharmacy in the form of:

• synonyms;
• generics;
• combined means.

The price category of these medications has a wide range. There are analogs of Dona that are cheaper and more expensive, but with an equivalent therapeutic result.

Table of Dona analogues with price and country of origin

A higher price for Dona analogues is observed among foreign manufacturers.

What else can replace Don, what effective analogues for the treatment of osteoarticular pathology? The list can be supplemented with the following medications:

• Glucosamine;
• Drastop;
• Sustagard arthro;
• Piaskledin;
• Artrocam;
• Injectran;
• Diaflex;
• Chondroitin;
• Flexamine;
• Sinagra.

A wide range of Dona analogs allows for effective treatment of diseases of the osteoarticular system not only for adults, but also for children.

Dona or Mukosat - which is better?

Manufacturer: JSC SINTEZ (Russia)
Release form: capsules, solution for intramuscular and intraarticular administration

Active ingredient: chondroitin sulfate

Mucosat is an analogue of Dona tablets. Both products are chondroprotectors that improve the structure of cartilage tissue and slow down degenerative processes in it. But their mechanism of action is different due to the difference in active substances.

The best drug would be Mucosat, since the analogue is well tolerated, has minimal and rare side effects and broader indications. It can be used in fractures to stimulate callus formation. Patients often choose Mucosat, since this analogue is cheaper than Don tablets, which is an important point during a long course of treatment.

Dona or Alflutop - which is better and more effective

Manufacturer: K.O.
BIOTECHNOS S.A. (Romania) Release form: solution for injection and intra-articular administration

Active ingredient: bioactive concentrate from small marine fish

Dona and Alflutop have chondroprotective, anti-inflammatory and analgesic effects, and have a positive effect on local metabolism in cartilage and bone tissue. This analogue of Dona in injections will be better and more effective for acute pain syndrome accompanying diseases of the joints or spine.

The drug has a rapid effect, especially when injected into a joint, which leads to a decrease in pain and an increase in the range of motion of the limb. This effect of using the analogue is confirmed by reviews from doctors.

Sinarta

The drug Sinarta contains glucosamine sulfate. One sachet contains 1.5 pure substances; the drug package contains 10 or 30 sachets. As excipients aspartame, polyethylene glycol and sorbitol. Produced in powder form for preparing a solution.

Despite the contraindications, Sinarta is one of the most effective analogues of Dona.

Glucosamine sulfate stimulates the action of glycosaminoglycans, has an anti-inflammatory effect, and slows down the process of degradation of cartilage tissue. The effectiveness of the drug can be assessed within three weeks after use.

Glucosamine is usually well tolerated and does not have a negative effect on systems and organs. About 90% of the drug is absorbed from the gastrointestinal tract, and the bioavailability of the drug is 26%. Sinarta is indicated in the treatment of osteoarthritis.

Use the product one sachet per day, dissolving the powder in a glass of water. It is advisable to drink the medicine with meals. Treatment time is from one to two months. On the recommendation of a doctor, when positive dynamics are achieved, treatment can be carried out in courses 2-3 times a year.

Contraindications to the drug are quite general - these are intolerance to glucosamine, pathologies of the liver and kidneys, and a tendency to bleeding. Due to the fact that the product contains aspartame, it is not recommended for use in patients with phenylketonuria.

IMPORTANT! The medicine is not recommended for patients with seafood allergies; the drug is prescribed to asthmatics with caution, and diabetics need to monitor their blood sugar levels when treated with Sustart.

Adverse reactions from the medication are flatulence, epigastric pain, constipation, diarrhea, nausea, dyspepsia, allergic reaction, skin rash, itching, dizziness and drowsiness.

Dona or Teraflex - which is better or more effective?

Manufacturer: BAYER PHARMA A.G.
(Germany) Release form: capsules

Active ingredient: chondroitin sulfate, glucosamine

Both drugs are in the group of stimulators of bone and cartilage tissue repair, have the same active substance glucosamine and restore their structure.

The Teraflex composition is enriched with a second active component, which makes it more effective. This combined property of the drug gives an anti-inflammatory and analgesic effect. This is equivalent to the use of analgesics and non-steroidal anti-inflammatory drugs. Teraflex will be the best for osteoarthritis with moderate pain.

If pain in the joint is severe, Dona injections will be more effective, as they quickly relieve acute pain.

Teraflex

Teraflex is one of the most effective and relatively cheap chondroprotective agents. The drug contains chondroitin and glucosamine. It helps relieve pain, improve the mobility of articular joints, and stimulates regenerative processes in cartilage tissue. Thanks to these properties, Theraflex significantly reduces the need for non-steroidal anti-inflammatory drugs.

The drug is indicated for osteochondrosis, osteoarthrosis and other degenerative pathologies of the spine. The drug is not recommended for hypersensitivity, in patients with renal failure, during pregnancy and lactation, as well as for children.

Take the capsules with a whole glass of water; the drug does not depend on the time of meal. In the first three weeks of treatment, one capsule is prescribed three times a day, then two capsules. Duration of therapy is from three to six months, treatment is repeated if necessary.

Teraflex is usually well tolerated by patients, but negative reactions may also occur: insomnia, abdominal pain, heaviness in the legs, tachycardia, allergic reactions. If abdominal pain occurs, the drug is discontinued.

Dona or Arthra - which is better?

Manufacturer: UNIFARM INC. (USA)
Release form: tablets

Active ingredient: glucosamine, chondroitin sulfate

Dona and Artra are used to treat joint diseases accompanied by a violation of the structure of cartilage tissue. Dona's analogue in tablets contains, in addition to glucosamine, chondroitin sulfate. The best drug for joints would be Artra, since the medication has more indications and fewer contraindications.

Both active ingredients enhance the action of each other, which leads to stimulation of the production of joint fluid and restoration of the damaged structure of synovial cartilage. The effectiveness of the analogue for osteoarthritis is confirmed by reviews from doctors who often prescribe Arthra for treatment.

Glucosamine Maximum

Medicine made in Russia. Available in tablet form. One package of the drug (plastic bottle) contains 60 tablets. Glucosamine Maximum contains glucosamine and chondroitin, which are natural elements of joint tissue. Glucosamine contains 750 mg, chondroitin – 250 mg.

The interaction of the components helps to quickly restore cartilage tissue in case of damage and degenerative processes. Glucosamine Maximum is prescribed for joint pain, inflammatory diseases and stiffness. Since the components of the drug are well tolerated, the only contraindication to the use of the drug is hypersensitivity.

Dona substitutes should be taken one tablet per day, preferably with meals. In this case, one hundred percent of glucosamine and sixty percent of chondroitin are absorbed from the medicine. The duration of treatment is two months, after which the achieved effect is assessed. Among the adverse reactions of the drug, allergic reactions may develop.

Dona or Sustilak - which is better?

Manufacturer: CELEBRITY BIOPHARMA LTD (India)
Release form: tablets

Active ingredient: glucosamine

Both products have the same active substance and mechanism of action on the cartilage tissue of the joints. Dona is a medicine that quickly relieves acute pain; it will be best for more pronounced destructive changes in the joint, preventing the patient from becoming disabled.

The therapeutic effect of using the Sustilak analogue manifests itself after a longer period of time. The drug can be used as a prophylaxis at the very initial manifestations of pathology and at any stage of development of joint destruction. In this case, Sustilak will be more effective in practical use.

Dona or Structum - which is better?

Manufacturer: PIERRE FABRE MEDICINE PRODUCTION (France)
Release form: capsules

Active ingredient: chondroitin sulfate

Dona and Structum are in the same pharmacological group, but act differently due to different active ingredients. Both drugs stimulate metabolism in cartilage tissue, slow down the progression of degenerative processes, and reduce joint pain.

Structum capsules will be more effective for osteoarthrosis and osteochondrosis of the intervertebral discs, as well as in the treatment of osteoarticular pathology. The drug is safer, can be prescribed to children over 15 years of age and has a minimum of contraindications. The results from its use last for a long time after the course of therapy.

Artradol

Another effective representative of chondroprotectors is Artradol. Artradol contains proteoglycans, which are involved in the construction of cartilage tissue. The distinctive ability of the drug Artradol is that it not only protects the joint from destruction, but is also capable of restoring muscle tissue cells.

And Artradol is also able to relieve inflammation and inhibit the process of decay in cartilage tissue. Thanks to the chondroprotector components, it has an antithrombotic effect and activates synovial and subchondral microcirculation. Thanks to this, the production of synovial fluid is stimulated.

Artradol is available in tablet form. Highly porous pills are actively dissolved in a special liquid and injected intramuscularly. The package contains 10 ampoules. The medicine is intended for the treatment of degenerative-dystrophic diseases of the joints.

Artradol is usually well tolerated by patients, but some patients may experience allergic reactions, and bleeding from small vessels at the injection site. Injections are contraindicated for pregnant women, women during lactation and children. Use with caution in patients with gastrointestinal pathologies and a tendency to bleeding.

The tablets should be taken every other day, 1 ml. From the fourth injection, you can double the volume of the drug if it is well tolerated by the patient. The course of therapy is at least 25 injections. If positive results from treatment are obtained, the course is repeated after six months. The medication is available by prescription.

Dona or Rumalon injections - which is better?

Manufacturer: ROBAPHARM EOOD (Bulgaria)
Release form: solution for injection

Active ingredient: glycosaminoglycan-peptide complex

Rumalon, an analogue of Dona in ampoules, is a combined product of animal origin that stimulates the synthesis of collagen and mucopolysaccharides, slows down the destruction of cartilage and restores it. Both medications are chondroprotectors, but act through different mechanisms.

When comparing drugs for the treatment of osteoarticular pathology, the best remedy would be Rumalon, which has broader indications and fewer side effects. The medication is well tolerated and effective, as confirmed by patient reviews.

Elbona

Manufacturer: NPO FARMVILAR (Russia)
Release form: solution for injection, powder for the preparation of solution for oral administration

Active ingredient: glucosamine

Elbona belongs to the group of correctors that regulate the metabolism of bone and cartilage tissue. This analogue of Dona has an anti-inflammatory and analgesic effect, prevents the destruction of cartilage tissue and promotes its restoration. Acting on the joint capsule, the drug increases its permeability and increases the range of motion in the joint.

Chondroglucide

Chondroglucide is produced by domestic companies. The release form is a gel for external use, packaged in tubes of 30 g. Chondroglucide contains 250 mg of glucosamine and 500 mg of chondroitin. Externally, the medicine is a thick gel-like substance, odorless, and the color ranges from white to yellowish. Excipients of the drug are sodium disulfide, lavender oil, propylene glycol, ethanol and other substances.

Chondroglucide belongs to the group of chondroprotectors and serves to stimulate cartilage tissue. It also has an analgesic and anti-inflammatory effect. Helps slow down destructive processes. Chondroitin sulfate in the drug is obtained from cattle cartilage; it suppresses the action of hyaluronidase and elastase, which affect the breakdown of cartilage tissue. Glucosamine also has protective agents, inhibiting phospholipase and collagenase, which destroy cartilage.

The drug is recommended for osteoarthritis. The gel is applied two to three times a day to the damaged joint with a strip 4 cm long, which corresponds to 2 g of the drug. Treatment must be continued for at least one month, after which the course is interrupted and, on the doctor’s recommendation, repeated again after a couple of weeks. Usually the drug is well tolerated, but an allergic reaction may occur on the surface of the skin.

The chondroprotector is contraindicated for use in children, pregnant women and during lactation, as well as in case of individual intolerance to the drug. Do not apply the medicine to damaged areas of the skin.

Chondrogard

Manufacturer: SOTEX CJSC (Russia)
Release form: solution for intramuscular and intraarticular administration

Active ingredient: chondroitin sulfate

Chondrogard is an analogue of Dona in injections. This is a high molecular weight mucopolysaccharide that has the properties to inhibit and reduce degenerative changes in cartilage tissue.

Under the influence of the medication, the inflammatory process of the synovial membrane of the joint is reduced, and phosphorus-calcium metabolism is restored. This process leads to a decrease in pain, relief of swelling and an increase in the range of active movements in the joint.

Artiflex

A drug from the group of chondroprotectors. The main active ingredient is glucosamine; the medicine also contains ibuprofen and allantoin. Additional components include glycerol monostearate, polysorbate, propylene glycol, mineral oil and other components. It comes in the form of a white cream and has a uniform consistency. Release volume – 20, 40 or 100 mg.

The combined medicine Artiflex is excellent for the treatment of diseases of the musculoskeletal system, has an analgesic and anti-inflammatory effect, and an antioxidant effect. Indicated for the treatment of inflammatory and degenerative-dystrophic changes in cartilage tissue, with a decrease in motor activity.

The drug is contraindicated for skin diseases - eczema, dermatosis, as well as in patients with a tendency to asthma. The cream is applied 2-3 times a day to the skin and rubbed well until the drug disappears from the surface. The course of treatment is two weeks.