Hyalurom solution for intra-articular injection 1.5% 2 ml syringe 1 pc. in Moscow


When are hyaluronic acid injections used?

Hyaluronic acid injections are used for general skin rejuvenation, as well as as individual procedures:

  • correction of nasolabial folds;
  • filling vertical wrinkles above the lips;
  • elimination of vertical wrinkles between the eyebrows;
  • restoration or giving additional volume to the lips and cheeks.

Hyaluronic acid injections are used to rejuvenate and restore the décolleté, arms and other areas of the body. Depending on the desired result, injections are administered to different depths of soft tissues and skin. Thanks to this cosmetic procedure, it is possible to quickly eliminate wrinkles, even out skin defects, change the shape of the face, the shape of the lips and much more.

Hyalurome CS (syn.liquid prosthesis 0.06/3ml+0.09/3ml No. 1 syringe)

A country

Romania
The country of production may vary depending on the batch of goods. Please check with the operator for detailed information when confirming your order.

Compound

Syringe 3 ml
Sodium hyaluronate 60.00 mg, sodium chondroitin sulfate 90.00 mg, sodium chloride 10.50 mg, sodium dihydrogen phosphate monohydrate 1.35 mg, disodium phosphate dodecahydrate 15.15 mg, sodium hydroxide and/or hydrochloric acid (for adjustment pH) up to pH = 7.4 ± 0.2, water for injection up to 3.00 ml.

pharmachologic effect

Hyalurom CS is a synovial fluid prosthesis, a sterile, transparent viscoelastic solution, which contains sodium hyaluronate 60 mg/3 ml and sodium chondroitin sulfate 90 mg/3 ml (registered in the Russian Federation on September 10, 2008, No. RU P N014581/01). Hyaluronic acid is the main component of synovial fluid, determining its viscoelastic properties. It forms a covering layer on the entire inner surface of the joint that protects the cartilage and synovial membrane from mechanical damage, as well as from free radicals and inflammatory factors. Chondroitin sulfate is one of the naturally occurring glycosaminoglycans (GAGs), consisting of the alternative sugar D-glucuronic acid and N-acetyl-D-galactosamine. Chondroitin sulfate is obtained in the form of sodium salt from the trachea of ​​cattle and is used for the preparation of active pharmaceutical ingredients. Chondroitin sulfate is a stimulator of tissue regeneration, promotes water retention and restoration of shock-absorbing functions in cartilage tissues. Promotes the synthesis and protection of collagen, which is the structural basis of all connective tissues, and also increases the production of hyaluronic acid in synovial cells, which has a beneficial effect on maintaining the viscosity of synovial fluid. The use of chondroitin sulfate together with sodium hyaluronate helps slow down degradation and stimulate cartilage regeneration.

Indications for use

- for the symptomatic treatment of mild, moderate or severe osteoarthritis; - for pain and limitation of mobility caused by degenerative-dystrophic or post-traumatic changes in the knee, hip and other synovial joints; — to relieve pain after arthroscopy (use is possible no earlier than 1 week after the intervention).

Mode of application

Hyalurome CS is intended for intra-articular administration. The solution should not be administered outside the joint cavity, or in patients with infections or skin diseases in the injection area. Intra-articular injection should be administered by specialists trained in intra-articular injection techniques and performed under aseptic conditions in medical institutions. It is possible to use local anesthetics before intra-articular injection, for example, subcutaneous administration of lidocaine. It is necessary to properly disinfect the injection site (use a 70% alcohol solution or other disinfectants). Disinfectants containing quaternary ammonium salts (for example, benzalkonium chloride) should not be used, as a precipitation reaction may occur. Before administering Hyaluroma CS, fluid should be removed from the joint cavity. It is recommended to perform arthrocentesis before administering the solution. After removing the protective cap from the syringe tip, attach a sterile needle to the syringe. Typically, for the knee joint, a needle measuring 0.8x40 mm (21G) is used; for other joints, we recommend using a needle of the required size (from 17G to 22G) depending on the joint. Hyalurome CS is injected into the joint in a volume depending on the size of the joint. The joint cavity should not be overloaded. Each pre-filled syringe is intended for single use. The contents of the syringe must be used immediately after opening. Unused solution cannot be stored and should not be re-sterilized. After injection of Hyaluroma CS, the patient is advised to adhere to a gentle regimen and avoid excessive or prolonged stress on the joints (for example, running or playing tennis) for 48 hours.

Side effect

Moderate pain and swelling in the injection area may occur. The above symptoms are transient and usually disappear after 72 hours.

Contraindications

— established hypersensitivity to the components of this medical device; — the presence of active inflammatory or infectious processes in the joint; - presence of signs of active skin disease or skin infection in the area of ​​the intended injection; - use in patients with an established diagnosis of an autoimmune disease or undergoing immunotherapy; - use during pregnancy or lactation; - age up to 18 years.

special instructions

Before use, check the expiration date and the integrity of the packaging. Do not use after the expiration date stated on the packaging. Use of open and/or damaged sterile packaging is not permitted. Needles and syringes used for injection should not be reused. Repeated sterilization is not permitted.

Dispensing conditions in pharmacies

On prescription

How does a hyaluronic acid injection work?

Rejuvenation with the help of this cosmetic product is considered a “friendly” procedure, since hyaluronic acid is a polysaccharide found in many tissues of the body. It is secreted by fibroblasts, but with increasing age, the secretion decreases, which invariably affects the skin.

Gels are produced based on hyaluronic acid, which immediately after being introduced into tissues begin to reconstruct their structure. In this case, all natural processes proceed without change. During the action of the acid, the skin becomes elastic, wrinkles are leveled out and become less noticeable. The skin becomes smooth.

The cosmetic effect of the procedure lasts from 6 months to a year. It depends on the type of skin and its characteristics. The patient’s lifestyle also affects the duration of the effect. Gradually, part of the acid is absorbed, and the rest is excreted from the body as a natural product, without causing irritation or an allergic reaction.

Procedures for rejuvenation with hyaluronic acid

After examination, the rejuvenation procedure is prescribed by a specialist. Injections are injected directly into problem areas where wrinkles and defects are clearly visible.

Types of medical procedures:

  • Mesotherapy is a therapeutic procedure for general skin rejuvenation and stimulation of wrinkle smoothing processes. During the procedure, microinjections with hyaluronic acid are injected under the skin of the face.
  • Contour plastic surgery – facial contours are corrected and wrinkles are smoothed out. The procedure involves introducing the active substance into problem areas.
  • Biorevitalization triggers the restoration of metabolic processes and the regenerating properties of the skin. The procedure is based on the use of hyaluronic acid injections.

The gel fills the voids, while deep folds are leveled and wrinkles are smoothed out. Externally, your face will look younger by about 10 years. This is a safer and less expensive method compared to plastic surgery.

Using injections, you can reinforce the oval of the face. In this case, the cosmetologist introduces hyaluronic acid according to a certain scheme, calculating it depending on the individual person. The composition of the cosmetic preparation, in addition to hyaluronic acid, also includes other substances that differ in the type of effect and duration of the effect.

Long-term fillers are usually 2 types of fillers: collagen and hyaluron. Both of these components are natural substances that are present in the connective tissue of every organism. The validity period of a collagen injection is from 2 to 4 months, hyaluronic acid from 6 to 9 months.

Fillers of a permanent or semi-permanent type are suspensions of tiny particles and a liquid or gel. These injections help eliminate folds and deep-lying facial wrinkles. The duration of the effect can last for 12-18 months.

Hyaluronic acid: course of injections

Preparation for the rejuvenation procedure involves cleansing the skin:

  • makeup removal;
  • disinfection;
  • use of painkillers.

Analgesic creams and topical preparations can be used as a pain reliever. There are often cases when pain relief involves applying a piece of ice to the puncture site. Some cosmetic products contain lidocaine, which eliminates sensitivity during the injection itself. Pain relief is not always required. In some cases, the procedure is painless.

After the preparatory steps, the doctor injects the drug into those places where correction is required. To distribute the filler, the doctor massages the injection site before the substance turns into a gel. In some cases, a cold compress is applied after the procedure to minimize swelling and bruising. The doctor warns that redness and swelling may appear at the injection site, which disappears after a few days. The specialist should warn that after injections of hyaluronic acid you should not:

  • be in the sun;
  • overheat;
  • perform physical activity.

Regularity of repeated injections

After the procedure, swelling appears at the injection site, which gives the impression of a slightly increased result. But this effect disappears after 2-3 days along with swelling. In some cases, bruising may occur; a cold compress will help reduce the likelihood of this and speed up its disappearance.

Injections are valid for 6-12 months, depending on the manufacturer of the drug and its composition. After this period, the drug will completely resolve, and the skin will return to its original appearance. But studies prove that you can achieve the most positive effect if you administer injections after 6-9 months and use special preparations for moisturizing and lifting the skin based on hyaluron.

Hyalurom solution for intra-articular injection 1.5% 2 ml syringe 1 pc. in Moscow

Release form

solution for intra-articular administration

Package

disposable syringe 2 ml

pharmachologic effect

Solution for intra-articular administration HYALUROM - 1.5% sodium hyaluronate solution in disposable 2 ml syringes is a sterile, viscoelastic solution of sodium hyaluronate. Sodium hyaluronate is obtained as a result of fermentation. Sodium hyaluronate HYALUROM is a polysaccharide identical to human, consisting of repeating disaccharide units of N-acetylglycosamine and sodium glucuronate, with a molecular weight exceeding 2,400,000 Da. Sodium hyaluronate is ubiquitous in the human body and is present in high concentrations in tissues such as the vitreous, synovial fluid, umbilical cord and dermis. In synovial fluid, sodium hyaluronate acts as a lubricant and shock absorber, promoting normal movement without pain. In a disease such as arthritis, the viscoelasticity of the synovial fluid decreases, so that the mechanical load on the joint significantly increases and the destruction of articular cartilage increases, manifested by limitation and pain when moving the joints. The lubricating and shock-absorbing effect of this drug alleviates pain and improves joint mobility when used intra-articularly. These effects continue for more than 6 months after one course of treatment.

Indications

HYALUROM solution is used as a viscoelastic additive to replace synovial fluid for pain caused by degenerative diseases of synovial joints, such as osteoarthritis or osteoarthritis. In its action, the drug HYALUROM serves as a lubricant and mechanical support for the diseased joint.

Directions for use and doses

HYALUROM solution is used as a viscoelastic additive to replace synovial fluid for pain caused by degenerative diseases of synovial joints, such as osteoarthritis or osteoarthritis. In its action, the drug HYALUROM serves as a lubricant and mechanical support for the diseased joint.

Compound

1 syringe contains: Active substances: sodium hyaluronate, sodium chloride, water for injection.

Contraindications

individual intolerance (including a history of hypersensitivity) to the components of the HYALUROM solution; the presence of infected wounds, abrasions in the joint area; infectious diseases of the joints; known systemic bleeding disorders. HYALUROM may contain traces of bacterial proteins and is contraindicated in patients with relevant hypersensitivity.

Side effects

Sodium hyaluronate has excellent tolerability. It is possible that local secondary effects such as pain, a feeling of warmth, redness and swelling may occur in the joint into which the drug is injected (applying ice to the joint for five to ten minutes will relieve all such phenomena). Allergic reactions can occur extremely rarely. When administered intra-articularly, there are minimal risks associated with infection and bleeding.

Storage conditions

Keep out of the reach of children.

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