MOVEX - instructions for use, price, reviews and analogues

Movex is a medicine that has chondroprotective properties. The drug is used to normalize bone and cartilage tissue. With long-term use of the medicine, it is possible to establish phosphorus-calcium metabolism, thanks to which a person stops degenerative processes.

Movex is based on glycosaminoglycans and proteoglycan - together they form a compound that, in its chemical composition, differs little from ordinary human cartilage. To achieve maximum results, long-term use of Movex is required.

pharmachologic effect

Movex is based on glucosamine, a natural building material for joints. The component accelerates the restoration processes in cartilage, protects them from damage, accelerates the regeneration process and normalizes the recovery process.

Regular use stops degenerative and pathological processes. These two substances make up the natural structure of cartilage, thanks to which it is possible to return the joints to their natural structure.

Glucosamine is a component that is a structural part of normal human cartilage tissue. When ingested, this substance promotes the accelerated production of proteoglycans. Also, such changes contribute to faster absorption of sulfates by the joints.

Pharmacological properties

Movex active has anti-inflammatory, analgesic, chondroprotective and regenerative effects.
slows down the process of damage to cartilage tissue and bone resorption, restores cartilage tissue, accelerates the formation of callus in case of injury, and helps restore joint function. Pharmacodynamics. Glucosamine is a substrate for the construction of articular cartilage and stimulates the regeneration of cartilage tissue. Any adverse effect (disease, age-related metabolic disorders, injuries) reduces its synthesis and concentration in connective tissue, which leads to disruption of the structure and function of joints and the appearance of pain. Glycosaminoglycans and proteoglycans are part of the complex matrix that makes up cartilage.

Glucosamine is part of the endogenous glycosaminoglycans of cartilage tissue, stimulates the production of proteoglycans and increases the absorption of sulfate by articular cartilage.

Thus, glucosamine replenishes the endogenous glucosamine deficiency. Takes part in the biosynthesis of proteoglycans and hyaluronic acid, which counteracts the progression of degenerative processes in the joints, spine and surrounding soft tissues; stimulates the formation of chondroitinsulfuric acid, normalizes the accumulation of calcium in bone tissue, helps restore joint function and eliminate pain.

Chondroitin sulfate is a high molecular weight mucopolysaccharide that affects phosphorus-calcium metabolism in cartilage tissue. It slows down bone resorption, cartilage degeneration processes and reduces calcium loss. It has a chondroprotective effect under normal conditions and in conditions of destruction of cartilage tissue, stimulates the regeneration of cartilage tissue, and has an anti-inflammatory and analgesic effect. Prevents compression of connective tissue, “lubricates” articular surfaces and normalizes the production of joint fluid.

Diclofenac potassium is an NSAID with analgesic, anti-inflammatory and antipyretic effects, has a rapid onset of action, which is especially important for the treatment of acute pain due to inflammation. The mechanism of action is based on inhibition of the synthesis of prostaglandins, which play a major role in the development of inflammation, pain and fever. The anti-inflammatory, analgesic and antipyretic properties of NSAIDs are associated with their ability to inhibit prostaglandin synthesis by blocking the synthesis of the COX enzyme. Reduces pain at rest and during movement, reduces the manifestations of morning stiffness in joints, swelling of soft tissues, improves the functional state of the musculoskeletal system. Diclofenac potassium suppresses predominantly the exudation phase, and to a lesser extent, proliferation, reducing collagen synthesis and associated tissue sclerosis.

Pharmacokinetics. Glucosamine sulfate. The bioavailability of glucosamine when administered orally is 25–26%. After distribution in tissues, the highest concentrations are determined in the liver, kidneys and cartilage tissue. About 90% of glucosamine, which enters the body when administered orally, in the form of glucosamine salt, is absorbed in the small intestine and enters the liver through the portal bloodstream. A significant portion of glucosamine that is absorbed is metabolized in the liver. Breaks down to urea, water and carbon dioxide. About 30% of the dose taken persists in the connective tissue for a long time. It is excreted mainly by the kidneys and in very small quantities in feces.

Chondroitin sulfate. After a single dose of chondroitin, Cmax in blood plasma is reached after 3-4 hours, in synovial fluid - after 4-5 hours. The concentration in synovial fluid exceeds that in blood plasma. The bioavailability of chondroitin sulfate is 13–15%. Excreted by the kidneys within 24 hours.

Diclofenac potassium does not accumulate. Cmax in blood plasma is achieved 2 hours after administration. Binding to blood plasma proteins is 99.7%. Penetrates into synovial fluid. Systemic clearance of the active substance is 263 ml/min. T½ from blood plasma - 1-2 hours. 60% is excreted by the kidneys in the form of metabolites, less than 1% - by the kidneys unchanged, the remainder - in the form of metabolites with bile.

Pharmacokinetics

The active components of this medicine are perfectly absorbed by the body. About 25% of glucosamine sulfate is rapidly absorbed by body tissues immediately after receiving the drug. The highest concentration of this substance is present in the kidneys, liver and cartilage tissue.

90% of glucosamine is absorbed by the small intestine and travels through the bloodstream to the liver. Under the influence of metabolites, the product breaks down to the state of urea, carbon dioxide and ordinary water.

30% of the active ingredients of the drug can be present for a long time in the connective tissues of the body. The components of the drug are excreted naturally through the kidneys and liver in the form of urine and feces.

Sodium chondroitin sulfate causes reactions in the body 3-4 hours after use, while its maximum concentration in the synovial fluid occurs after 5 hours. This component is completely eliminated by the body in just 25 hours.

Movex comfort instructions and frequently asked questions

Stock

active ingredients: glucosamine sulfate, sodium chondroitin sulfate;
1 tablet containing glucosamine sulfate 500 mg, sodium chondroitin sulfate 400 mg;

additional ingredients: microcrystalline cellulose, anhydrous silica, talc, croscarmellose sodium, sodium starch glycolate (type A), hypromelose, polyethylene glycol 6000, titanium dioxide (E 171), tartrazine (E 102), ethyl cellulose.

Medicine form. Tablets, sealed with film.

Main physical and chemical properties: yellow-colored tablets, oval-shaped, double-shaped, scored on one side, coated.

Pharmacotherapeutic group. Make sure that the musculoskeletal apparatus becomes ill when it becomes stagnant. Non-steroidal anti-inflammatory and anti-rheumatic agents.

ATX code M01A X.

Pharmacological power.

Pharmacodynamics.

Glucosamine is a substrate for the development of subglobular cartilage and stimulates the regeneration of cartilage tissue. Glucosaminoglycans and proteoglycans are part of the foldable matrix that makes up cartilage.

Glucosamine enters the warehouse of endogenous glycosaminoglycans of cartilage tissue, stimulates the production of proteoglycans and increases the depletion of sulfate by cartilage.

Thus, glucosamine replenishes endogenous deficiency of glucosamine. Take part in the biosynthesis of proteoglycans and hyaluronic acid, which prevents the progression of degenerative processes in the joints, spine and excess soft tissues; stimulates the creation of chondroitinsiric acid, normalizes the deposition of calcium in bone tissue, promotes the renewal of global functions and the reduction of pain syndrome.

Sodium chondroitin sulfate has a chondroprotective effect, stimulates the regeneration of cartilage tissue, and has an anti-inflammatory, analgesic effect. Sodium chondroitin sulfate, which contributes to phosphorus-calcium metabolism in cartilage tissue, and high molecular weight mucopolysaccharide (mw 20,000–30,000). The drug increases the resorption of cartilage tissue and reduces the loss of calcium, increasing the process of degeneration of cartilage tissue. It overcomes the tightness of the fabric, “smoothes” the moist surfaces and normalizes the ventilation of the moist area.

Pharmacokinetics.

Glucosamine sulfate. The bioavailability of glucosamine when administered orally is 25–26%. After the division of tissues, the highest concentrations are found in liver, nirka and cartilaginous tissue. Approximately 90% of glucosamine, which is available to the body orally, in the form of glucosamine salt, is absorbed from the small intestine and passes through the portal circulation to the liver. The vagoma part of the glucosamine, which is soaked up, is metabolized by the liver, breaks down to waste, water and carbon dioxide. Approximately 30% of the administered dose persists for three hours in the tissue. Excreted head-to-head with nirkas and in very small quantities - with feces.

Chondroitin sulfate sodium. After a single dose of chondroitin, the maximum concentration in blood plasma (Cmax) is reached after 3–4 years, in the synovial region – after 4–5 years. The concentration in the synovial fluid exceeds the concentration in blood plasma. The bioavailability of sodium chondroitin sulfate becomes 13–15%. Be in nirk for 24 years.

Clinical characteristics.

Showing

Degenerative-dystrophic illness of the slopes and ridges; primary and secondary osteoarthritis, osteochondrosis, humeroscapular periarthritis; fractures (for faster healing of callus).

Contraindicated

Increased sensitivity to any of the components of the drug, impaired liver function or at the stage of decompensation, bleeding to the point of bleeding. Do not use the drug if you have an allergy to shellfish.

Interactions with other medicinal agents and other types of interactions .

With one-hour stagnation, the absorption and concentration of tetracyclines in the serum may increase, but the clinical significance of such an interaction has not been established; The infusion of penicillins and chloramphenicol may change.

When the drug is stagnated, the need for non-steroidal anti-inflammatory drugs decreases.

The drug can enhance the action of anticoagulants (oral vitamin K antagonists, including warfarin), which will require monitoring of laryngeal symptoms during one-hour stagnation. Blood concentrations may be affected by cyclosporine and warfarin.

Features of stagnation.

Do not overdo the recommended dose.

We treat patients with blood sugar diabetes and patients with poor glucose tolerance should monitor the level of sugar in the blood much more often and during the period of drug withdrawal.

In patients with a known risk factor for cardiovascular disease, it is recommended to monitor the level of lipids in the blood in case of episodes of hypercholesterolemia during treatment with glucosamine.

When treating asthma, the drug should be administered with caution, as such patients may be more susceptible to developing allergic reactions to glucosamine and may worsen the symptoms of their illness.

Immobilize the body under the supervision of a doctor for patients with thrombophlebitis.

Patients with nicotine and liver insufficiency should be treated with caution.

In rare cases, patients with cardiac and/or neuronal insufficiency were careful to avoid swelling and/or loss of water in the body. This may be due to the osmotic effect of chondroitin sulfate.

It is recommended to use 2.2 mmol sodium per tablet. Be careful in congested patients who are treated with controlled sodium instead.

Barvnik tartrazine (E 102) may cause allergic reactions.

Suspension during pregnancy or breastfeeding.

Due to the fact that clinical data indicate the effectiveness and safety of the drug during pregnancy or breastfeeding, the drug should not be frozen during this period.

This is due to the fluidity of the reaction during treatment with vehicles or other mechanisms.

The fluidity of the reaction to the infusion of the drug during treatment with vehicles or other mechanisms was not carried out. Be careful when using transport means and work that requires respect. Once the drug is taken, you may experience drowsiness, drowsiness, confusion and/or blurred vision, which can be avoided when using vehicles or other mechanisms.

Method of congestion and dosage

Take the tablets internally with a small amount of radish.

During the first 3 years, take 1 tablet 3 times per dose; nadali – 1-2 tablets 2 times a day for 3 months. Repeat the course 2-3 times per river.

For the doctor's reasons, treatment may be trivial.

Children.

Due to the fact that the drug has been administered to children as young as 24 hours of age, it is not recommended.

Overdose

It is possible to reduce side effects. In case of overdose, symptomatic treatment is recommended.

Adverse reactions.

On the side of the scolio-intestinal tract: dyspepsia, nausea, vomiting, pain in the epigastric region, diarrhea, constipation, intestinal bloating.

On the side of the skin and structures: dermatitis, hair loss.

On the side of the immune system: allergic reactions, including skin rashes, mottled weed, hyperemia, eczema, itching, angioedema.

On the other hand, the nervous system and organs are sensitive to: headache, mental weakness, drowsiness, insomnia, fatigue, confusion, disturbed vision.

Inshi: bump.

All side effects disappear after treatment.

Term of attribution . 3 rocks.

Save your mind.

Keep out of the reach of children in the original packaging at a temperature not exceeding 25 °C.

Package.

30, 60 or 120 tablets per pack, 1 pill per cardboard package;

2 drops of 60 tablets in a cardboard package.

Release category. Over the counter.

Virobnik.

Meditop Pharmaceutical Ltd.

The locality of the distributor and the addresses of the locality for the promotion of its activities.

Ugorshchina, Edі Endre Yu. 1., Pilisborosieno, 2097.

Applicant.

Movi Health GmbH.

The applicant's location.

35 Jägerstrasse, Baar, 6340, Switzerland.

Compound

Glucosamine sulfate is the most important active ingredient in Movex. This component is responsible for restoration processes in bone tissue, accelerates the production of synovial fluid and prevents bone loss. The composition also contains diclofenac sodium and chondroitin sulfate.

These components are essential for maintaining healthy connective tissue. With any damage, these substances slow down in production, which causes their deficiency. A person is faced with a pain syndrome that gradually increases. To establish the regeneration of damaged tissues, therapy is carried out with Movex tablets.

Cost and release form

Movex is a fairly powerful drug that is highly popular among patients. It is usually prescribed to slow down degenerative processes in tissues. The product is produced by an Indian company in two forms:

Movex Active - tablets of 30 or 60 pieces, the average cost of which is 1000-1600 Russian rubles;
Movex Comfort - tablets of 30 or 60 pieces, which can be purchased for 800 or 1400 Russian rubles.

Movex Comfort

Name: Movex Comfort Pharmacological action: Movex Comfort is a chondroprotective drug containing chondroitin sulfate and glucosamine.

Glucosamine is a substance that is part of cartilage tissue. When taken orally, glucosamine replenishes the deficiency of endogenous glucosamine, stimulates the regeneration of cartilage tissue, reduces the negative impact of various factors on the structure of cartilage and helps restore mobility and function of joints. Glucosamine is a structural part of endogenous glycosaminoglycans, stimulates the synthesis of proteoglycans and increases the absorption of sulfate by articular cartilage. Glucosamine prevents the development of degenerative processes in the cartilage of joints, the spine and soft tissues, normalizes calcium deposition in bone tissue, and also helps reduce pain and restore joint function. Chondroitin sulfate has a pronounced chondroprotective effect, improves reparative processes in joint tissue, and has an anti-inflammatory and analgesic effect. Chondroitin sulfate regulates phosphorus-calcium metabolism, reduces bone resorption and slows down degenerative processes in cartilage tissue. Chondroitin sulfate takes part in the synthesis of joint fluid, ensuring normal lubrication of articular surfaces.

After oral administration, the bioavailability of glucosamine is about 26%, chondroitin sulfate is about 15%. Glucosamine undergoes first pass effect through the liver and is metabolized to urea, carbon dioxide and water. Maximum concentrations of glucosamine are observed in the liver, cartilage tissue and kidneys. About 30% of glucosamine is present in connective tissue for a long time. Peak plasma concentrations of chondroitin sulfate are observed 3-4 hours after administration, peak concentrations in synovial fluid are achieved within 4-5 hours. The level of chondroitin sulfate in synovial fluid is higher than that in plasma. Glucosamine is excreted mainly by the kidneys, some part is excreted by the intestines. Chondroitin sulfate is excreted by the kidneys.

Indications for use: Movex Comfort is used to treat patients suffering from osteoarthritis. Movex Comfort is also prescribed to patients with glenohumeral periarthritis, chondromalacia of the patella, fractures, as well as conditions that are accompanied by degenerative-dystrophic lesions of the articular cartilage.

Directions for use: Movex Comfort is taken orally. The tablets should be taken with 50-100 ml of drinking water, regardless of meals. The duration of the course of therapy and the dose of Movex Comfort are determined by the doctor. Patients over the age of 12 years are usually recommended to take 1 Movex Comfort tablet three times a day. After 3 weeks, it is recommended to switch to a maintenance dose of 1-2 Movex Comfort tablets twice a day. The total duration of treatment is 3-4 months. If necessary, the course is repeated several times a year. Do not exceed the recommended dose of Movex Comfort.

Side effects: When taking the drug Movex Comfort, the development of side effects was recorded in patients very rarely. Among the registered undesirable effects of the drug Movex Comfort, pain in the epigastric region, diarrhea, flatulence, constipation and nausea are described. In addition, when taking Movex Comfort, patients may develop allergic reactions, headaches and insomnia.

Contraindications: Movex Comfort is not prescribed to patients with intolerance to the active or auxiliary components of the tablets. Movex Comfort is contraindicated in patients with phenylketonuria, thrombophlebitis, bleeding tendency and diabetes mellitus. In pediatric practice, the drug Movex Comfort is used only in the treatment of patients over 12 years of age. You must be careful when driving a car or unsafe equipment during treatment with Movex Comfort.

Pregnancy: The use of the drug Movex Comfort during pregnancy and lactation is undesirable.

Interaction with other drugs: Movex Comfort increases the absorption of tetracycline antibiotics when used in combination. There is a decrease in the absorption of penicillins and chloramphenicol when used simultaneously with the drug Movex Comfort. When taking Movex Comfort, the need for non-steroidal anti-inflammatory drugs is reduced.

Overdose: When taking excessive doses of Movex Comfort, the risk of developing side effects characteristic of chondroitin sulfate and glucosamine increases. If you overdose on Movex Comfort tablets, you should consult a specialist.

Release form: Movex Comfort coated tablets, packaged in 30 or 60 pieces in polymer bottles, 1 bottle in a cardboard pack. Movex Comfort coated tablets, packaged in 60 pieces in polymer bottles, 2 polymer bottles in a cardboard box.

Storage conditions: Movex Comfort must be stored out of the reach of children, where the temperature is maintained from 15 to 25 degrees Celsius. The shelf life of Movex Comfort tablets is 3 years.

Synonyms: Teraflex, Chondroflex, Artra.

Composition: 1 coated tablet Movex Comfort contains: Glucosamine sulfate – 500 mg; Chondroitin sulfate – 400 mg; Auxiliary components.

Attention! The description of the drug " Movex Comfort " on this page is a simplified and expanded version of the official instructions for use. Before purchasing or using the drug, you should consult your doctor and read the instructions approved by the manufacturer. Information about the drug is provided for informational purposes only and should not be used as a guide to self-medication. Only a doctor can decide to prescribe the drug, as well as determine the dose and methods of its use.

Indications for use

Movex is a drug that represents a group of chondroprotectors. It is designed to protect cartilage tissue from destruction. The product has a combined effect and has a positive effect on the functioning of the entire body.

High efficiency from the use of the drug is ensured due to its unique composition. The medicine is based on glucosamine and chondroitin. In a mutual reaction, the components of the active substance react with each other, due to which the cartilage tissue is restored in a person.

Movex’s action is also aimed at normalizing the chemical properties of synovial fluid.

The active components ensure that it constantly maintains a viscous, dense consistency. They reduce the activity of elastase and hyaluronidase, which have a destructive effect on the structure of cartilage tissue.

With an integrated approach, you will be able to normalize calcium-phosphorus metabolism, thereby stopping the process of bone loss. This helps slow down destructive processes, a person gets rid of inflammation and can lead a full life.

Movex is usually used in the following cases:

Subsequently, injuries, intense physical activity that caused damage to bone or cartilage tissue;
For pathological processes in bones: osteopathic dysfunction, osteochondropathy, chondromalacia, periarthritis;
With degenerative changes in the spinal column or joints;
To significantly accelerate the rate of healing of fractures;
For the prevention of primary and secondary osteoarthritis, osteochondrosis, spondyloarthrosis.

Indications

Treatment of diseases of the musculoskeletal system, which are accompanied by signs of inflammation, pain, degenerative-dystrophic changes in the cartilage tissue of the joints and spine, decreased joint mobility; osteoarthritis, periarthritis (including knee, hip joints, intervertebral osteochondrosis, spondyloarthrosis), rheumatoid arthritis, fractures and injuries (to accelerate the formation of callus), post-traumatic inflammation of soft tissues and the musculoskeletal system (due to sprains, impacts).

Mode of application

Using this medicine is quite simple; to understand all controversial issues, study the instructions for use in detail. The tablets are intended for oral use. They need to be washed down with plenty of water, and this does not need to be tied to meals.

During the first 3 weeks of treatment, you need to take 1-2 tablets of the drug per day; in the future, it is advisable to increase the dose of the active substance. On average, the duration of treatment is 3 months; longer treatment should be discussed with your doctor.

To achieve the best results, treatment with Movex should be carried out 2-3 times a year.

Note!

Description of the drug Movex Comfort tablet. p/o No. 60 on this page is a simplified author’s version of the apteka911 website, created on the basis of the instructions for use.
Before purchasing or using the drug, you should consult your doctor and read the manufacturer's original instructions (attached to each package of the drug). Information about the drug is provided for informational purposes only and should not be used as a guide to self-medication. Only a doctor can decide to prescribe the drug, as well as determine the dose and methods of its use.

Side effects

Movex is a fairly safe drug that has a positive effect on the functioning of the body. It extremely rarely causes side effects, usually due to improper use of the drug.

Among the negative consequences of using the drug are:

Headache and dizziness;
Nausea and vomiting;
Lack of appetite;
Diarrhea and constipation;
Severe pain in the stomach area;
The appearance of allergic reactions;
Insomnia and nervousness;
Impaired concentration.

Contraindications

To prevent negative consequences, it is necessary to stop using Movex if there are contraindications. The manufacturer does not recommend taking this product in the following cases:

In case of individual intolerance to components or hypersensitivity to them;
With developing thrombophlebitis or phenylketonuria;
With an increased tendency to bleeding;
For diabetes and other endocrine diseases;
In children under 12 years of age.

To prevent side effects, read the instructions for use in advance. It is strictly forbidden to take Movex if there are contraindications.

special instructions

Do not exceed the recommended dose.

At the beginning of treatment in patients with diabetes, it is advisable to monitor blood glucose levels. Use only under medical supervision in patients with thrombophlebitis. Use with caution in patients with renal and hepatic insufficiency.

Use during pregnancy and lactation. Due to the fact that there are no clinical data on the effectiveness and safety of the drug during pregnancy and lactation, the drug should not be used during this period.

The ability to influence reaction speed when driving vehicles or other mechanisms. Studies on the effect of the drug on the reaction rate when driving vehicles or other mechanisms have not been conducted. If drowsiness, fatigue, dizziness and/or visual impairment occur while using the drug, you should refrain from driving vehicles or other mechanisms.

Overdose

If Movex is used incorrectly, a person may experience an overdose. Most often, it manifests itself in the form of an exacerbation of all side effects, but if the dose is exceeded too much, the patient develops other, more serious pathologies. These include thrombotic complications, optic neuritis, inflammatory process in the gastrointestinal tract, and the opening of internal bleeding.

To get rid of signs of overdose, you need to immediately induce vomiting to cleanse the stomach and take sorbents. If necessary, call an ambulance.

Features of application

You should not take Movex simultaneously with penicillin antibiotics - this significantly reduces their absorption, which reduces the effectiveness of such therapy. If you take the tablets together with tetracycline antibiotics, the concentration of active substances in the blood increases.

You should not take Movex together with anticoagulants or glucocorticoids - as a result of a chemical reaction, dangerous components are formed that cause abnormalities in the body's functioning.

Analogs

Movex is a fairly expensive product that is not supplied to all pharmacies. There are its complete analogues, which are no less effective. You can always replace this drug:

Actinak 100;
Remisid;
Ameolin;
Indomethacin;
Ketonal.

Remisid

Indomethacin

Ketonal

Reviews

Vasily, 44 years old, Volgograd “When I underwent a health examination, a specialist said that I was developing osteochondrosis. I didn’t think much of it right away, but after a few months I encountered serious pain. I consulted a doctor who advised me to take a course of Movex. After only 3 months I was able to return to a full-fledged lifestyle and got rid of constant nagging pain. I recommend this product to everyone, it really works.”

Igor, 36 years old, Voronezh “Several years ago I broke my leg and could not recover for a long time. Even after complete fusion, I continued to limp due to discomfort. The doctor advised me to take Movex. I took these pills for about 3 months, but after a few weeks I felt significant relief. By the first month I was free of pain at rest, and by the end of the second month I was free of discomfort during active activities. The only thing I didn’t like was a slight heartburn after use.”